Machine perfusion strategies in liver transplantation
نویسندگان
چکیده
منابع مشابه
Myocardial perfusion characteristics during machine perfusion for heart transplantation.
BACKGROUND Optimal parameters for machine perfusion preservation of hearts prior to transplantation have not been determined. We sought to define regional myocardial perfusion characteristics of a machine perfusion device over a range of conditions in a large animal model. METHODS Dog hearts were connected to a perfusion device (LifeCradle, Organ Transport Systems, Inc, Frisco, TX) and cold p...
متن کاملA simplified subnormothermic machine perfusion system restores ischemically damaged liver grafts in a rat model of orthotopic liver transplantation
UNLABELLED BACKGROUND Liver donor shortages stimulate the development of strategies that incorporate damaged organs into the donor pool. Herein we present a simplified machine perfusion system without the need for oxygen carriers or temperature control, which we validated in a model of orthotopic liver transplantation. METHODS Rat livers were procured and subnormothermically perfused with ...
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BACKGROUND Static cold storage is generally used to preserve kidney allografts from deceased donors. Hypothermic machine perfusion may improve outcomes after transplantation, but few sufficiently powered prospective studies have addressed this possibility. METHODS In this international randomized, controlled trial, we randomly assigned one kidney from 336 consecutive deceased donors to machin...
متن کاملHypothermic Machine Perfusion in Kidney Transplantation: Back to the Future?
Static cold storage is currently the most used method of organ preservation worldwide. However, cutting edge technology and dramatic changes in the donor pattern have lately renewed the interest toward hypothermic machine perfusion. Marginal and cardiac death donors show higher rates of primary non function and delayed graft function compared to standard criteria donors. In this setting, machin...
متن کامل“In-Site” Perfusion Technique for Rinse Solution in Liver Transplantation
lash or rinse solution use in liver transplantation has Fgathered much interest to prevent ischemia-reperfusion injury. Several solutions have been applied for clinical testing, but they remain controversial. Pratschke et al recently reported from a prospective randomized multicenter trial using Tacrolimus rinse based with histidine-tryptophanketoglutarate preservation solution for marginal liv...
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ژورنال
عنوان ژورنال: HepatoBiliary Surgery and Nutrition
سال: 2019
ISSN: 2304-3881,2304-389X
DOI: 10.21037/hbsn.2019.04.04